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Pharmaceuticals

Pharmaceutical Industry

Pharmaceutical (and nutraceutical) products that are ingested, or applied topically to the body, e.g. to the skin, can be assessed for quality, efficacy and customer acceptance through texture analysis.

Medications to be chewed, crushed, broken apart or dissolved are required to break down easily to aid delivery/ingestion or dosage. These tablets, pills and capsule products must also be resilient enough to withstand transport, handling and packaging processes without breakage. The impact of formulation changes to facilitate the desired oral administration characteristics may be evaluated by repeatable testing and analysis methods. Providing preferable sensory qualities is a major benefit in products of this nature, as consumers often have an aversion to taking medication.Gel capsules rupture

Lotions, ointments, creams and powders, which involve skin contact have many similarities to cosmetics, in terms of functional application – flow, spreadability, rate of absorption and ease of delivery. The texture affects finger feel, with smoothness and degree of oiliness influencing customer preference.

Dispensing from or opening the container is also significant with medical and health products: for comprehensive test solutions in the consumer packaging client sector, visit Mecmesin Corporation.

Test methods for the pharmaceutical sector 

CompressionTablet crush

Tablets can be evaluated for hardness and resistance to damage when being packaged or transported. The compressive force required to crush, or reduce to powder for ingestion within another carrier, for example to administer to a child or pet.

  • Spreadability and ease of application of ointments and creams
  • Forward extrusion, dispensing effort of creams and gels

 

ExtrusionOintment spreadability

Used for semi-solids, forward or back extrusion can assess the characteristics of flow, consistency and spreadability, influnced by ingredient viscosity.

  • Ensure consistent dispensing rates and forces for alternative formulations
  • Spreadability and ease of application of moisturisers, hair waxes, masks and pastes (e.g. toothpaste)
  • Forward extrusion, dispensing evaluation of creams, shampoos

  

Penetration and punctureHard lozenge penetration

Solid tablets or lozenges can be tested for hardness with narrow diameter cylinder probes or needles.

  • Tablet or lozenge hardness, bite force, crush resistance
  • Rate of softening studies – throat lozenges dissolved in the mouth

 

Shear, snap, bend and break
Tablet snap

Larger tablets, or those with a scored line or indent to aid snapping, can be tested for the effort needed to break.

Contact us for more information about specialist fixture design.

  • Tablet snapping force

 

 

TensionCosmetics tension

  • Cream, ointment stickiness

  

 

 

 

Gel testingGel testing

Some pharmaceutical and nutraceutical products include gelling agents in their formulations, as an alternative to creams of for the inherent properties of a gel. Gel industry standard tests for the raw ingredient or the final gel product, may be performed to evaluate the strength.

  • Bloom strength testing

Trusted by customers across the world

I have been working with FTC for the past 3 years, we bought in that lapse of time 2 texture analyzers with different probes fixtures for all kind of applications at our Monterrey Plant. We have always been able to count on the technical support of FTC who kindly answers our requests in a prompt manner and with the best disposition.

As we continue developing our process to achieve better results at our company, we will for sure rely on FTC for technical support and equipment upgrades that will deliver us the best possible results.

Claudia Rojas, Hershey Monterrey Plant - Mexico
Asst. Staff Scientist
https://www.hersheys.com

As a Meat Scientist and program leader for the University of Nevada, Reno, I need to ensure that equipment I use in my lab is reliable, durable, versatile, and accurate. For texture analysis of meats, there are many systems available in the market. Over the last 15 years of my career, I¹ve worked with many of them and had great and bad experiences with different brands.

Last year, I decided to try a different system for my lab, the TMS-Pro Texture Analyzer from Food Technology Corporation. The system has all the attributes I was expecting to conduct texture and shear force analysis in a quick and not complicated way. The customer support provided by them is outstanding and their technicians are always ready to walk me through new procedures and initial set up. If you are looking for a reliable system for food texture analysis and special customer service, the TMS-Pro is the system to go for and the Food Technology Corporation is the one that can deliver the support.

Amilton de Mello
Assistant Professor of Agriculture, Meat Science and Food Safety
https://www.unr.edu/anvs

Excellent customer service. Consistently followed up and offered help without asking. Relatively low priced - provides good value. 

Easy to switch different load cells. Used it for 5 lab sessions for 68 students this semester and performed well.

 

 

Professor Jeyam Subbiah, University of Nebraska
https://nebraska.edu/