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Pharmaceuticals

Pharmaceutical Industry

Pharmaceutical (and nutraceutical) products that are ingested, or applied topically to the body, e.g. to the skin, can be assessed for quality, efficacy and customer acceptance through texture analysis.

Medications to be chewed, crushed, broken apart or dissolved are required to break down easily to aid delivery/ingestion or dosage. These tablets, pills and capsule products must also be resilient enough to withstand transport, handling and packaging processes without breakage. The impact of formulation changes to facilitate the desired oral administration characteristics may be evaluated by repeatable testing and analysis methods. Providing preferable sensory qualities is a major benefit in products of this nature, as consumers often have an aversion to taking medication.Gel capsules rupture

Lotions, ointments, creams and powders, which involve skin contact have many similarities to cosmetics, in terms of functional application – flow, spreadability, rate of absorption and ease of delivery. The texture affects finger feel, with smoothness and degree of oiliness influencing customer preference.

Dispensing from or opening the container is also significant with medical and health products: for comprehensive test solutions in the consumer packaging client sector, visit Mecmesin Corporation.

Test methods for the pharmaceutical sector 

CompressionTablet crush

Tablets can be evaluated for hardness and resistance to damage when being packaged or transported. The compressive force required to crush, or reduce to powder for ingestion within another carrier, for example to administer to a child or pet.

  • Spreadability and ease of application of ointments and creams
  • Forward extrusion, dispensing effort of creams and gels

 

ExtrusionOintment spreadability

Used for semi-solids, forward or back extrusion can assess the characteristics of flow, consistency and spreadability, influnced by ingredient viscosity.

  • Ensure consistent dispensing rates and forces for alternative formulations
  • Spreadability and ease of application of moisturisers, hair waxes, masks and pastes (e.g. toothpaste)
  • Forward extrusion, dispensing evaluation of creams, shampoos

  

Penetration and punctureHard lozenge penetration

Solid tablets or lozenges can be tested for hardness with narrow diameter cylinder probes or needles.

  • Tablet or lozenge hardness, bite force, crush resistance
  • Rate of softening studies – throat lozenges dissolved in the mouth

 

Shear, snap, bend and break
Tablet snap

Larger tablets, or those with a scored line or indent to aid snapping, can be tested for the effort needed to break.

Contact us for more information about specialist fixture design.

  • Tablet snapping force

 

 

TensionCosmetics tension

  • Cream, ointment stickiness

  

 

 

 

Gel testingGel testing

Some pharmaceutical and nutraceutical products include gelling agents in their formulations, as an alternative to creams of for the inherent properties of a gel. Gel industry standard tests for the raw ingredient or the final gel product, may be performed to evaluate the strength.

  • Bloom strength testing

Trusted by customers across the world

My first contact with FTC was through buying texture analyzer equipment as my area of interest is Rheology. We faced a problem operating the appliance. The company tried hard to help us through the internet, but the University thought it was better to send me to the company branch located in England. I received a highly advanced training course for 10 days free of charge. They provided me with programs that operate the equipment along with the information needed.

It was a great effort and outstanding support. I would like to thank Shirl Lakeway and FTC for providing me with this opportunity and for his continuous help. Finally, I encourage researchers who are interested in the physical properties of foods and dairy to choose FTC as it is a respectable and dependable company and offers the best deals concerning prices and training with different languages, such as Arabic for the Middle East.

Professor Hoda El-Zeini, Dairy Science and Agriculture University - Cairo, Egypt
Professor
https://cu.edu.eg

The University of Arizona’s Nutritional Sciences Food Lab acquired a Texture Analyzer from Food Technologies about 5 years ago. The company has a great product, which is tailored to food needs. 

We have used the Texture Analyzer for both research projects and as a tool to demonstrate to students how food manufacturers can employ objective testing in product evaluation to show how differing ingredients in the same product can affect quality attributes. Its use adds another dimension to the foods labs.

Drew Lambert has been instrumental in helping with set up for testing and providing support whenever there’s a question. He has been a pleasure to work with and is always accommodating with our needs and schedules.  He has even sent us special attachments for special projects.  We couldn’t ask for a better technical support.  Thanks for a great product and great service.

Patricia Sparks, Ph.D.
Assistant Professor of Practice
https://www.arizona.edu

Nestle purchased a texture system from Food Technology Corporation in 2006. Since then I have recommended the texture system to several vendors in North and Central America. Staff at FTC was able to develop a simple training manual and procedure for the texture system allowing easy training in short period of time.

From purchasing of equipment through to installation and start-up, the level of personal care and service was remarkable. Shirl Lakeway and his staff at Food Technology Corporation are patient and understanding, and are always at our disposal for any assistance. Since we bought the equipment we have had no problems and feel very secure knowing that we can count on FTC for their support and service.

Dr Mawele Shamaila, Nestle - USA
http://www.nestleusa.com/